Maturity Onset Diabetes of the Young (MODY) is non-insulin dependent diabetes with
onset < 25 years with autosomal dominant inheritance. It is a monogenic form of
diabetes characterized by autosomal dominant mode of inheritance, onset of
diabetes below 25 years of age and impaired insulin secretion is a major henotypic trait.
Different subtypes due to mutations in different genes. Till date 14 MODY subtypes have been described, caused by mutations in various genes such as
- Hepatocyte Nuclear Factor 4a (MODY1)
- GCK (MODY2)
- HNF 1a (MODY3)
- Insulin Promoter Factor 1 (MODY4)
- HNF 1 b (MODY5)
- Neuro D1 (MODY6).
In the majority of the populations studied, MODY3 is the most prevalent type of MODY
and is caused by various mutations in HNF 1a gene, If affected maturity onset type 2
diabetes, MODY. If so,Please fill up
the form below:
Consent Form – Mandatory to fill up
It is mandatory to fill this before any genetic testing has done.
MODY Registration Form